Inflammasomes in Pathophysiology of Acute Pancreatitis: “Et Facta Est Lux”

When Hans Chiari invented the term auto digestion little was known about pancreatic pathophysiology. However, that concept posed more questions than it explained up until recently. In 2000 a major medical breakthrough, the discovery of the inflammasome took place and in the last decade its role in inflammation was researched in great detail. This discovery could be the hidden link in the defussyfication