NK-Cell Count and Its Function in Producing Interferon Gamma Associated with the Cervical Cancer Natural History

Objective: Natural killer cell (NK-cell) has an important role in tumor immunosurveilance. We investigate the NK-cell count and its function in producing IFN-γ on normal cervix, subclinical high risk-HPV (hr-HPV) infection, precancerous lesion, and cervical cancer in order to understand the natural history of uterine cervical cancer.