Tobacco Use Accelerates Biological and Functional Lung Aging

Keywords Lung aging; Tobacco; FEV1; FENO; DLCO Editorial The lung has two main functions. The first is respiratory function dependent on ventilatory mechanics and gas exchange, which is well correlated with the possibilities of using oxygen and producing carbon dioxide (the respiratory quotient) [1]. The second is non-respiratory functions represented by metabolic, immunological, and endocrine ones. Pulmonary aging will result in reduced efficiency of all these functions [1,2].