Impact of the Embryonated Chicken Egg Isolation Process Used For Avian influenza Viruses on Subsequent Characterization of Viral Hemagglutinin Gene

Virus isolation is critical for the detailed characterization of Avian influenza Viruses (AIVs). In general, AIVs are isolated by inoculating embryonated chicken eggs with the specimens suspected of containing the virus. The characteristics of the AIVs in the original specimens, however, may