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Volume - 1 Edition - 1 (Jan - Mar)

Case Report
Published On: January 26, 2018

A Very Rare Case of Intra-cardiac Lymphoma Presenting as Splenic and Renal Infarcts

Shah S1*, Daboul N2, Lee D2 and Mewawalla P2
Primary lymphomas of the heart are extremely rare, accounting for less than 2% of all primary cardiac tumors. Histologic confirmation is fundamental in developing an early treatment plan, facilitating improved prognosis. Clinical presentation is heterogeneous and generally related to the affected cardiac chamber. The right atrium and right ventricle are the two most frequently involved sites [1]. Arterial and/or venous embolic...

Mini Review
Published On: January 26, 2018

New Insight for the Treatment of Follicular Lymphoma in Relapse: The Role of Obinutuzumab

Maher Salamoon*
In patients who relapse early in the course of treatment, patients with low grade lymphoma need new standards since most patients become resistant to subsequent treatment. A number of novel therapies are being examined in this setting, including monoclonal antibodies, immunoconjugates, immunomodulatory agents, and signal transduction inhibitors. Recently, with data accumulation treatment options moved...

Commentary
Published On: January 26, 2018

Transfusion Ratio of Plasma to Packed Red Blood Cells Yields Better Outcomes in Both Trauma and Surgical Patients

Mohamed Rahouma MD*, Mohamed Kamel MD, Leonard N. Girardi MD, Mario Gaudino MD, FEBCTS
In our prior meta-analysis, on the proper transfusion ratio of fresh frozen plasma (FFP): packed red blood cell (RBC) that included 16,607 patients from 36 studies, we found that lower ratio was,associated with less 24-h and 30-day survival (OR=2.41, 95% CI=1.94-3.01 and OR= 1.74, 95%,CI=1.51-2.02 respectively) with a ratio of 1:1.5 gave the best 24-hour and 30-day survival benefit,(OR=0.25, 95% CI=0.09-0.7...

Editorial
Published On: March 22, 2018

Application of Nanomaterials in Oncology

Kumar R*
Cancer is the next to cardiovascular disease as a cause of death in several parts of the world. Cancer is a man-made disease by modern industrialisation. It should be noted that nothing in the natural environment can cause cancer. Pollution, adulteration of foods, change in food and life styles massively...

Review Article
Published On: April 30, 2018

Role of Mesenchymal Cells and Immunosuppressive Cells within Inflammatory Tumor Microenvironment

Mohamed Adil AA, Anandraj V, Kumar S, Waseem M, Chitra K, Kumar BA, Jamal S and Ahmed N*
In recent years, cancer microenvironment comprises of several kinds of immune factors associating to the group of tumor environment. The role of mesenchymal stem cells (MSCs) and regulatory T cells (Tregs) play a vital factor in the immune environment....