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Research Article
Published On: September 9, 2020

Lung Aging Related to Oxidative Stress and Mitochondrial Biogenesis in COPD Patients

Amani S*, Ines S, Bernard G and Sonia R
Aims: To identify the physiological and pathological (COPD) non-respiratory lung aging by determining gene expression changes in the airways of genes encoding antioxidants and of mitochondrial biogenesis' markers. Methods: Three groups were recruited: group I (7 healthy-young-controls, mean age=36.8 years), group II (10 healthy-elderly, mean age=68.7 years) and group III (10 elderly-COPD, mean age=68.7...

Published On: December 29, 2020

Tobacco Use Accelerates Biological and Functional Lung Aging

Rouatbi S*
Keywords Lung aging; Tobacco; FEV1; FENO; DLCO Editorial The lung has two main functions. The first is respiratory function dependent on ventilatory mechanics and gas exchange, which is well correlated with the possibilities of using oxygen and producing carbon dioxide (the respiratory quotient) [1]. The second is non-respiratory functions represented by metabolic, immunological, and endocrine ones. Pulmonary aging will result in reduced efficiency of all these functions [1,2]....