Introduction: During interplanetary missions, space crews will have to adapt to unusual environments with restrictive living conditions like the unprecedented situation appeared on Earth
to stay in good health and benefit from their experiences in an optimal way. Mental, behavioral and physical health is the goal of our studies in extended periods of time. Method: The ethological approach was used to monitor behavioral manifestations of well being and
stress feeling of confined crews in various ground experimental paradigms (MDRS-14d, SIRIUS-120d, CELSS-180d and MARS-520d). The emphasis was on temporal factor...