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Volume - 2 Edition - 1

Research Article
Published On: April 12, 2019

Blockage of Tumor Necrosis Factor α Versus CD80/86 Signaling on the Response to Influenza Vaccination of Rheumatoid Arthritis Patients

Jane Kasten-Jolly*, Nataliya Yuklyaeva, Jennifer Victory, Melissa Scribani, Erica Lasek-Nesselquist, Afeefa Shahnawaz, Donald Raddatz and David A. Lawrence
The objective of the study was to compare and characterize the response to the 2014/2015 season influenza vaccine in patients with Rheumatoid Arthritis (RA) receiving biological agents, either TNF α blockers or a T-cell activation blocker, abatacept...

Review Article
Published On: October 29, 2019

The Minor T Cell Subsets in Blood may not be Minor in Helping to Assess Human Health

Kasten-Jolly J and Lawrence DA*
The CD4+ T cells referred to as helpers or Major Histocompatibility Complex Class II (MHCII)- responsive cells and CD8+ referred to as cytolytic or MHCI-responsive T cells are the major subsets in human blood. However, minor subsets of T cells exist in blood and may have usefulness in assessing health and response to environmental stresses...